Advances in Clinical Outcome Assessments
نویسندگان
چکیده
منابع مشابه
Developing Personalized Clinical Outcome Assessments
In recent years, patients, advocates, researchers, regulators, and other stakeholders have highlighted the importance of engaging patients more directly in medical product development and the regulatory review process. A key focus of these efforts has been advancing the science of patient input: identifying rigorous, systematic approaches to incorporating patient perspectives in medical product...
متن کاملBarthel Index and Clinical Outcome in Elderly
Objectives: Among the elderly patients who are admitted in emergency departments, there is a sub-population of frail elderly who needs particular attention. The purpose of this study was to explore relationship between Barthel index and clinical outcome in elderly patients aged over 60 during a week follow up after initial admission. Methods & Materials: The method was a prospective cohort s...
متن کاملAlternate endpoints and clinical outcome assessments in pediatric ulcerative colitis registration trials.
OBJECTIVES Presently, there is no consensus on endpoint measures to assess clinical outcomes for pediatric ulcerative colitis (UC). This study reviewed the endpoints used in the registration trials of approved drugs for pediatric UC. METHODS The primary efficacy endpoints of all registration trials completed from 1950 to 2008 that led to Food and Drug Administration approval for indications i...
متن کاملOutcome measures for oral health based on clinical assessments and claims data: feasibility evaluation in practice
BACKGROUND It is well known that treatment variation exists in oral healthcare, but the consequences for oral health are unknown as the development of outcome measures is still in its infancy. The aim of this study was to identify and develop outcome measures for oral health and explore their performance using health insurance claims records and clinical data from general dental practices. ME...
متن کاملBest (but oft-forgotten) practices: expressing and interpreting associations and effect sizes in clinical outcome assessments.
This article reviews methods used to facilitate the interpretation and evaluation of group-level differences in clinical outcome assessments. These methods complement and supplement tests of statistical significance. Examples, including studies in nutrition, are used to illustrate the application of the interpretation methods for group-level comparisons from experimental or observational studie...
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ژورنال
عنوان ژورنال: Therapeutic Innovation & Regulatory Science
سال: 2015
ISSN: 2168-4790,2168-4804
DOI: 10.1177/2168479015607286